Hey everyone! Researchers from the Weizmann Institute of Science in Israel have uncovered a fascinating process where breast cancer cells enter a 'sleep mode,' hiding in the body for years before reawakening. Think of it like your favorite app going into standby mode, only to surprise you later with a burst of energy! 😮
The study reveals that these cells mimic a natural cycle normally seen in healthy breast tissue, where cells shift from a rapid growth phase to a more stable, mature stage. By boosting levels of a protein called OVOL, researchers managed to put the highly aggressive triple-negative breast cancer cells into dormancy. In experiments with mice, this approach slowed down tumor growth, offering promising clues for future treatments.
However, there's a twist. While OVOL helps suppress cell division initially, its decline—possibly due to hormonal changes like lower estrogen levels—could trigger a dangerous reawakening of the cancer cells. Additionally, the dormant cells accumulate unstable molecules called free radicals, which can damage DNA and compromise the cell's repair systems, making the disease harder to treat once it returns.
This breakthrough adds a new dimension to cancer research by emphasizing the importance of the dormant stage. Understanding this process could pave the way for therapies that prevent cancer from making a comeback, even years after remission. Stay tuned for more updates on this exciting development! ✨
Reference(s):
cgtn.com
